INDOLIZINE-2-CARBOXYLIC ACID Property

Melting point:

240-241 °C (decomp)

Density 

1.28±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

pka

1.60±0.41(Predicted)

Safety

Risk Statements 

36/37/38

Safety Statements 

26-28-37/39

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

INDOLIZINE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

Uses

Indolizine-2-carboxylic Acid is used to prepare acylaminophenyloxazoles as inosine monophosphate dehydrogenase inhibitors. It is also used to synthesize indolizine-2-carboxamides as potential HIV-1 protease inhibitors.